Greek flag English flag


Xanthelasma is a group of yellowy-orange nodular patches that grow beneath the surface of the skin, around the upper and lower eyelids near the inner canthus. They accumulate cholesterol-rich fluid inside and are soft to touch.


The size of these fatty plaques can range from 2 mm to 30 mm and most of the time they tend to consolidate and multiply. Over time, the Xanthelasma continues multiplying in number, growing in volume, becomes permanent, and unfortunately do not regress on their own.

Although these are harmless and malignant, they are in many cases deformable and need to be removed.

Xanthelasma occurs mainly in middle-aged women

Women aged between 40-60 are more likely to develop Xanthelasma. However, even teenagers or elderly people cannot be excluded.

The appearance of Xanthelasma is often accompanied by high levels of lipids in the blood (hyperlipidemia). They are still more common in people with familial hypercholesterolemia (FH). This, however, is not the norm since more than 50% of those with Xanthelasma have low cholesterol, triglyceride and lipids in the blood.

Additional factors ‘favouring’ the appearance and/or recurrence of Xanthelasma are smoking, obesity, high blood pressure, diabetes, abnormally high levels of lipids and high cholesterol.

Individuals with Xanthelasma have a higher risk of myocardial infarction, ischemic heart disease and atherosclerosis.

Their visual diagnosis is done by a dermatologist who will examine the skin around the eye and recommend cholesterol and triglyceride control.

Xanthelasma is a form of Xanthoma

Xanthoma develops into a small bump where it grows in volume and size and becomes nodular. It appears mainly in places where there is persistent pressure, such as in the knees, joints, tendons, elbows, palms, soles and buttocks, and can extend from 2.5 to 7.5 cm.

Xanthoma is a symptom of an underlying metabolic disease that increases blood lipids. It contains enough cholesterol for Xanthoma to occur in people who have high cholesterol from birth.

Efficient elimination with LASER CO2

At IQ-Intensive Quality Dermatology clinics, we effectively apply LASER CO2 to effectively eliminate Xanthelasma.

The LASER CO2 removal method is non-invasive, safe and painless. The LASER energy selectively aims at the target leaving the healthy areas around the perimeter intact and it also doesn’t leave any scars or marks. The application is performed by an experienced dermatologist in the comfort of the dermatological clinic and healing plus the return to normal activities are immediate.

If you belong to the high-risk group for the appearance or recurrence of Xanthelasma, you should follow the steps below:

  • Reduce cholesterol
  • Change eating habits
  • Drink light to moderate alcohol
  • Keep a healthy body weight
  • Do physical exercise
  • Limit the consumption of saturated fats
  • Stop smoking

You should visit Dermatology IQ – Intensive Quality Dermatology if:

You observe any accumulation of fat below or above your eyelids as it is very likely the beginning of Xanthoma.

About the author:

Christofer Tzermias

Specialised in the UK (Oxford & London) and in North America (New York & San Diego) in the field of LASER Dermatology, Dr Tzermias, has been providing dermatological state-of-the-art treatments using cutting-edge LASER and Energy based Devices for over 20 years. He has been Director of Interventional and LASER Dermatology Department at the Athens Medical Center for over 18 years and for the last 9 years is the Scientific Director of IQ - Intensive Quality Dermatology & Cosmetic Surgery Clinics, which at the 2017 Healthcare Awards won the ‘Innovation Award for Innovative Services’ for their pioneering contributions. Since 2018, IQ Dermatology & Cosmetic Surgery Clinics has also been operating in London, UK and in Muscat, Oman. Dr Tzermias is a Fellow of the world-renowned American Society for LASER Medicine and Surgery (ASLMS), a Founder Member of the European Society LASER Dermatology (ESLD), the Vice President of the ‘Open Health Alliance’ and he is also on the Board of Directors of Elitour - Greek Medical Tourism Council.

Most read articles

Greek Flag


49, Vas. Sofias Avenue, Athens
Metro station “Evangelismos”
Parking: Polis Park (Rizari)

Τ: 210 72 42 600
    210 72 34 230


Greek flag


71, Kifissias Avenue, Maroussi
Attiki Odos Ring Road
(Exit 11 “Kifissias” – Towards Athens)
15 parking spaces
Suburban Railway “Kifissias” station

Τ: 210 61 00 900

English Flag


33 Cavendish Square, Marylebone

Τ: +44 (0) 20 8144 8494


We are open every day,
Monday – Friday, 9:00 – 21:00
Saturday, 10:00 – 16:00


tuv certification

elitour certification